![]() ![]() Validation was performed experimentally with a Maquet 190 one-liter test lung (Getinge, Solna, Sweden) using VC ventilation with a 0.5-s inspiratory hold. The accuracy of the dynamic method was tested by comparing paired C rs and R rs values predicted by the dynamic method and the static method (used here as the ‘gold standard’) for the same breath. 2 defining the values for C rs and R rs for the breath under consideration Here ‘b’ represents the unique solution of Eq. Projecting path A onto the C rs – R rs plane results in a two-dimensional function ( B) relating C rs to R rs. This path is defined by surface values coinciding with the measured P aw, with point ‘a’ referring to the still unknown solution of Eq. P aw, also measured at t k and equal in this example to 27 cmH 2O, further restricts the solution of Eq. 2 for a given set of Δ V, F aw, and PEEP a measurements made at time t k during insufflation. This surface encompasses all possible combinations of P aw, C rs and R rs capable of satisfying Eq. min −1, and PEEP a = 5 cmH 2O and shown graphically as a three-dimensional surface bounded by C rs values ranging from 10 to 50 mL.In this example, the solution matrix was developed for Δ V( t k) = 300 mL, F aw( t k) = 32 L Schematic of the numerical method used to solve the respiratory system equation of motion for static compliance ( C rs) and airway resistance ( R rs). These findings support to the possibility of using the dynamic method in continuously monitoring respiratory system mechanics in patients on ventilatory support with volume-controlled ventilation. ![]()
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